Welcome to DOJOLVI®
DOJOLVI® is the first and only prescription drug available as a source of calories and fatty acids in Canada for children and adults with long-chain fatty acid oxidation disorders.
Select a type to learn more.
Welcome to DOJOLVI®
The first and only FDA-approved treatment for children and adults with long-chain fatty acid oxidation disorders.
Select a type to learn more.
STARTING DOJOLVI
UltraCare® Patient Services is here to help you with:
- Reimbursement Navigation
- Educational Support
- Adherence Support
- Financial Support
- Pharmacy Services
- Bilingual Support
A completed Enrollment Form is required for enrollment in UltraCare Patient Services. Talk to your healthcare team.
TAKING DOJOLVI
Download this step-by-step guide to discuss with your healthcare professional how to store, administer, and keep track of DOJOLVI doses.
Download the Guide
LC-FAOD defined.
WHAT ARE LC-FAOD?
Long-chain fatty acid oxidation disorders (LC-FAOD) are rare inherited disorders that prevent the body from breaking down long-chain fatty acids into energy during metabolism.
Each type of LC-FAOD is named for the specific enzyme that is affected.
People living with LC-FAOD have difficulty producing enough energy because of their body’s inability to use long-chain fatty acids as an energy source during times of:
- Fasting
- Illness
- Prolonged exercise
Select a type to learn more.
VLCAD
(very long-chain acyl-CoA dehydrogenase) deficiency
Meet DOJOLVI (triheptanoin).
WHAT IS DOJOLVI?
DOJOLVI is used as a source of calories and fatty acids to treat adults and children with long-chain fatty acid oxidation disorders (LC-FAOD).
How does DOJOLVI work?
The body usually uses glucose (sugar) for energy; however, when all the glucose is used up, the body also gets energy from fat. People with LC-FAOD cannot use long-chain fat for energy. DOJOLVI is a source of medium chain fatty acids. It can provide energy to the body in two ways:
- by working around the process to break down long chain fatty acids into energy; and
- by providing another source of energy.
Talk to your healthcare professional to learn more about DOJOLVI.
WHAT IS DOJOLVI?
Taking DOJOLVI (triheptanoin).
ALWAYS TAKE DOJOLVI EXACTLY AS YOUR LC-FAOD HEALTHCARE PROFESSIONAL ADVISES
To help avoid side effects and ensure proper use, talk to your healthcare professional before you take DOJOLVI.
Talk to your healthcare professional before you take DOJOLVI. Talk about any health conditions or problems you may have, including if:
- you have feeding tube problems. Feeding tubes can breakdown over time. It is possible that using DOJOLVI with a feeding tube might also contribute to its breakdown. Check the feeding tube regularly to ensure it is not damaged and is working properly;
- you have pancreatic insufficiency. This is a condition where the pancreas does not make enough enzymes to help digest food properly;
- you or your partner are pregnant or planning to get pregnant;
- you are breastfeeding or plan to breastfeed.
Tell your healthcare professional about all the medicines you take, including any drugs, vitamins, minerals, natural supplements or alternative medicines.
The following may interact with DOJOLVI:
- Medicines called pancreatic lipase inhibitors, which act on enzymes in the gastrointestinal tract. An example is the medicine orlistat.
- A medicine used to treat seizures, bipolar disorder or migraines called valproic acid.
How to take DOJOLVI:
- Take DOJOLVI:
- exactly as directed by your healthcare professional.
- by mouth or give through a feeding tube. Follow the step-by-step instructions listed below. If you are not sure, contact your healthcare professional.
- 4 or more times throughout the day with a meal or snack. You will take DOJOLVI about every 3 to 4 hours.
- Mix it with liquid or soft food. Taking DOJOLVI on its own may cause side effects.
- Tracking your doses, especially as you start taking DOJOLVI, can help you get used to and continue with your treatment plan. It can also help your healthcare professional decide if changes to your dose are needed.
- If you are taking another medium-chain triglyceride (MCT) product, you must stop before your first dose of DOJOLVI.
- Your healthcare professional will tell you:
- how much DOJOLVI to take;
- how much liquid or soft food to use.
- They may also recommend that you increase the amount of fats that you eat in your diet.
- Do not mix or give DOJOLVI with plastic items made of polystyrene or polyvinyl chloride (PVC).
- Only use DOJOLVI with supplies (including feeding tubes) made of:
- stainless steel,
- glass,
- high or low density polyethylene,
- polypropylene,
- polyurethane, and
- silicone.
- Check all your supplies (including the feeding tube, if applicable) regularly. This is to ensure they are not broken or damaged in any way and that the feeding tube is working properly.
If you miss a dose (one of the portions taken throughout the day), take the next dose as soon as possible. If it is not possible to take all the doses for the day, skip the missed dose.
Speak to your healthcare professional and see the Patient Medication Information for more information.
Instructional Dosing Videos
Precautions
Press-in Bottle Adapter
Syringe Dosing
Syringe Cleaning
Dosing Cup
Dosing Cup CleaningInstructional Mixing Videos
storing dojolvi
Store the DOJOLVI bottle upright between 15 – 30°C. Do not freeze.
Once the bottle of DOJOLVI has been opened, use it within 9 months or by the expiration date on the bottle, whichever is earlier. There is a place on the DOJOLVI labels to write the date the bottle is opened.
Do not use or store DOJOLVI in containers made of polystyrene or PVC.
Keep out of reach and sight of children.
dosing guide
Information to discuss with your healthcare team on how to store, administer, and keep track of DOJOLVI doses.
Download the Guide
TRACKING DAILY DOSES
Tracking your doses, especially as you start taking DOJOLVI, can help you get used to and continue with your treatment plan. It can also help your healthcare professional decide if changes to your dose are needed.
Track your doses in 3 easy steps.1
2
3
EXAMPLE: Not actual patient data; for illustrative purposes only.
Download the Daily Dosing Tracker to discuss with your healthcare team >
WORKING WITH YOUR HEALTHCARE PROFESSIONAL
All patients treated with DOJOLVI should be under the care of clinical specialists knowledgeable in appropriate disease-related dietary management based upon current nutritional recommendations.
These specialists, which may include metabolic geneticists, dietitians, and nurse practitioners, will work together as your healthcare team and:
- May start you on a lower dose of DOJOLVI and increase the dose slowly over a few days or weeks. Babies may need a higher dose of DOJOLVI, since they may need more fats in their diet.
- Ensure you are receiving frequent monitoring and nutritional counseling appropriate to your specific needs when taking DOJOLVI
